University of California, San Diego researchers developed 3D printed implants for rats with spinal cord injuries, enabling them to regain function of their hind limbs

Briefing

University of California, San Diego researchers developed 3D printed implants for rats with spinal cord injuries, enabling them to regain function of their hind limbs

January 28, 2019

Briefing

  • 3D Printed Spinal Implant – Researchers at University of California, San Diego 3D printed spinal cord implants that restored function in hind limbs of rats with spinal cord injuries
  • Advanced Bioprinting Technique – Adopted microscale continuous projection printing (μCPP), which can print biological materials 1,000 times faster and at higher resolutions than traditional 3D-printing
  • Biocompatible Material – Used hydrogel called polyethylene glycol–gelatin methacrylate which is compatible with spinal axons, part of nerve cell (neuron) that carries nerve impulses away from cell body
  • Microchannels – Scaffold contains 200-micrometer microchannels to guide nerves, which are then filled with neural stem cells to encourage axon growth
  • Human-Size Implants – Also printed human scaffolds with size estimated from MRI scans
  • Next Steps – Conduct more studies on materials and structures, experiment on larger animals, and perform human trials in five years (2024)

Accelerator

Sector

Healthcare/Health Sciences

Organization

University of California - San Diego

Source

Original Publication Date

January 17, 2019

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