Briefing:
- AI-Based Drug Discovery – London-based Benevolent AI and American startup Insilico Medicine are using artificial intelligence to find potential cure to inhibit spread of 2019 corona virus
- Potential Drug – Benevolent AI identified one drug (janus kinase inhibitor baricitinib), already being used to treat rheumatoid arthritis, can potentially keep virus from infecting the body
- How It Works – Drug can strengthen protein called AAK1 in regulating ACE2, protein on cells of kidney, blood vessels and heart that is susceptible to viral infection
- Clinical Trial – Recommends clinical trial of drug on portion of affected patients as it is safer than other medicines considered
- Other AI Work – Insilico Medicine identified six molecules using AI that can potentially be exploited to create treatment, publishing their work so other medicinal chemists can study further for possible use
- Released Genome – Chinese scientists have sequenced genome of the virus which they shared to international community to discover potential vaccine and treaments
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Image Source: The Lancet
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Image Source: The Lancet
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