Briefing
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Bioinformatics startups Benevolent AI and Insilico Medicine using artificial intelligence to discover and accelerate treatments for corona virus

February 12, 2020

Briefing:
  • AI-Based Drug Discovery – London-based Benevolent AI and American startup Insilico Medicine are using artificial intelligence to find potential cure to inhibit spread of 2019 corona virus
  • Potential Drug – Benevolent AI identified one drug (janus kinase inhibitor baricitinib), already being used to treat rheumatoid arthritis, can potentially keep virus from infecting the body
  • How It Works – Drug can strengthen protein called AAK1 in regulating ACE2, protein on cells of kidney, blood vessels and heart that is susceptible to viral infection
  • Clinical Trial – Recommends clinical trial of drug on portion of affected patients as it is safer than other medicines considered
  • Other AI Work – Insilico Medicine identified six molecules using AI that can potentially be exploited to create treatment, publishing their work so other medicinal chemists can study further for possible use
  • Released Genome – Chinese scientists have sequenced genome of the virus which they shared to international community to discover potential vaccine and treaments

Image Source: The Lancet

Image Source: The Lancet
Sector: Healthcare/Health Sciences
Function: Research and Development
Organizations: Insilico Medicine Inc., BenevolentAI
Source: 

Original Publication Date: February 10, 2020

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