Chinese researchers discovered in new study that gene editing technique CRISPR-Cas9 does not cause off-target mutations in monkeys

Briefing

Chinese researchers discovered in new study that gene editing technique CRISPR-Cas9 does not cause off-target mutations in monkeys

June 22, 2018

Briefing

  • Safe CRISPR Method – New study by Chinese researchers discovered gene editing method CRISPR-Cas9 does not produce off-target mutations in rhesus macaque monkeys
  • Tested on Monkeys – Injected CRISPR-Cas9 into 30 zygotes or fertilized eggs, 24 of which developed normally and were implanted into six female monkeys, two of which got pregnant, with four of five babies surviving
  • Study Results – Sequenced whole genomes of baby monkeys and found that CRISPR gene modification worked in all but one, with CRISPR not creating de novo mutations (DNM), mutations that are not inherited
  • Disclaimer – Study not yet officially published or peer-reviewed

Accelerator

Sector

Healthcare/Health Sciences

Source

Original Publication Date

June 19, 2018

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