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Briefing
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- Cellular Reprogramming – Researchers at Salk University demonstrated cellular reprogramming process boosted mice lifespan by 30% and reversed aging in some tissues
- Methodology – Involved reprogramming adult cells into pluripotent stem cells, which can transform into different kinds of cells by controlling exposure to proteins regulating gene expression (i.e. four Yamanaka transcription factors), introducing antibiotic drug for two days and withholding it for five days
- Lab Tests – Partial reprogramming expanded mice’s lifespan from 18 weeks to 25 weeks on average without causing tumors, while procedure also rejuvenated muscle tissue and pancreas cells of middle-aged mice and reversed aging of human cells in lab
- Human Trials Way Off – Will take long time before they can be tested on people
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Accelerator
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Sector
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Healthcare/Health Sciences
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Organization
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Salk Institute for Biological Studies
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Source
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Original Publication Date
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January 13, 2017
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