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Briefing
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- Mini-Kidney – Researchers from National Technology University (NTU) grew mini-kidney one to two millimeters wide in lab from stem cells derived from skin cells of patient with genetic polycystic kidney disease
- Drug Testing – Lab-grown kidney also developed fluid-filled cysts, characteristic of genetic polycystic kidney disease, which were reduced in size upon testing two drug molecules
- Personalized Medicine – Can lead to individualized treatment for patients as traditional drug screening does not account for genetic or inherited causes
- Scientific Discoveries – May be used to study development of nephrons (i.e. kidney’s filtering units) in humans, as studies found high number of nephrons at birth is related to less incidences of hypertension and kidney failure in later life
- Organ Replacement – Researchers discovered kidney organoids still functioned when implanted in mouse, leading to potential organ replacements in future
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Accelerator
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Sector
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Healthcare/Health Sciences
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Organization
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Nanyang Technology University
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Source
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Original Publication Date
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August 19, 2019
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