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Briefing
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- Virus-Resistant Pigs – Researchers from Jilin University in China successfully genetically modified pigs to be resistant to classical swine fever virus (CSFV)
- Two Techniques – Used two techniques, gene editing CRISPR, which allows researchers to cut and paste edits to genome, and RNA interference, which silences gene expression
- CSF Virus – Deadly highly contagious virus that kills pigs within few weeks and still widespread in world except for North America, Australia and much of Europe where vaccines have already been developed
- Testing – Researchers split pigs into two rooms, one room with three gene-edited pigs and one virus-containing pig, while the other room has three un-edited pigs and one virus-containing pig
- Results – Gene edited pigs were still infected but symptoms were less severe and non-fatal, with lower virus numbers proliferating in bloodstream
- Next Generation Immunity – Virus resistant traits passed on to at least first generation of edited pigs’ offspring
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Accelerator
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Sector
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Agriculture, Forestry and Fishing
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Organization
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Jilin University
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Source
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Original Publication Date
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January 13, 2019
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