CRISPR off-switch proteins can improve accuracy and safety of gene editing, preventing unintended consequences

Briefing

CRISPR off-switch proteins can improve accuracy and safety of gene editing, preventing unintended consequences

January 18, 2017

Briefing

  • CRISPR gene editing off switch – Scientists discovered proteins that turn off CRISPR-Cas9 gene editing system, blocking SpyCas9 which act as DNA clipper from targeting specific genes in bacteria and engineered human cells
  • Improved accuracy – Can lead to more precise control of gene editing, preventing genes from being cut accidentally while able to boost or switch off gene activity temporarily
  • Enhanced safety – Provides fail safe way to block harmful use of technology such as making of biological weapons with scientists able to halt CRISPR gene editing outside lab

Accelerator

Sector

Healthcare/Health Sciences

Organization

University of California - San Francisco

Source

Original Publication Date

December 29, 2016

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